Anti-LDLR Polyclonal Antibody

品牌：solarbio | 货号：K106578P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106578P-50ul	solarbio	50ul	960.00元
K106578P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-LDLR Polyclonal Antibody
别名 FH;FHC;LDLCQ2;LDLR
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 120kDa
Gene ID 3949
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human LDLR
性状 液体
Public Immunogen Range A synthetic peptide of human LDLR
Subcellular Locations Cell membrane Cell surface Early endosome Endomembrane system Golgi apparatus Late endosome Lysosome Membrane Single-pass type I membrane protein clathrin-coated pit
Swiss Prot P01130
克隆类型 Polyclonal Antibody
背景资料 The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia

英文名称	Anti-LDLR Polyclonal Antibody
别名	FH;FHC;LDLCQ2;LDLR
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	120kDa
Gene ID	3949
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human LDLR
性状	液体
Public Immunogen Range	A synthetic peptide of human LDLR
Subcellular Locations	Cell membrane Cell surface Early endosome Endomembrane system Golgi apparatus Late endosome Lysosome Membrane Single-pass type I membrane protein clathrin-coated pit
Swiss Prot	P01130
克隆类型	Polyclonal Antibody
背景资料	The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia