Anti-MAGEA10抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-MAGEA10抗体

Anti-MAGEA10抗体

商家询价

产品名称: Anti-MAGEA10抗体

英文名称: MAGEA10

产品编号: YB--6816R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-MAGEA10抗体

产品编号 YB-6816R
英文名称 MAGEA10
中文名称 黑色素瘤相关抗原10抗体
别    名 Cancer/testis antigen 1.10; CT1.10; MAGE 10 antigen; MAGE10; Melanoma antigen family A 10; Melanoma associated antigen 10; MAGAA_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  免疫学  信号转导  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAGEA10:241-340/369 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011]. 

Function:
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. 

Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. 

Similarity:
Contains 1 MAGE domain. 

SWISS:
P43363

Gene ID:
4109

Database links:
UniProtKB/Swiss-Prot: P43363.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications